Skip to main content

Recent Publications

Dickey research neurodegeneration
  • Mutant huntingtin impairs PNKP and ATXN3, disrupting DNA repair and transcription. Gao R, Chakraborty A, Geater C, Pradhan S, Gordon KL, Snowden J, Yuan S, Dickey AS, Choudhary S, Ashizawa T, Ellerby LM, La Spada AR, Thompson LM, Hazra TK, Sarkar PS. Elife. 2019 Apr 17;8. pii: e42988. doi: 10.7554/eLife.42988.
  • AKAP1 Protects from Cerebral Ischemic Stroke by Inhibiting Drp1-Dependent Mitochondrial Fission. Flippo KH, Gnanasekaran A, Perkins GA, Ajmal A, Merrill RA, Dickey AS, Taylor SS, McKnight GS, Chauhan AK, Usachev YM, Strack S. J Neurosci. 2018 Sep 19;38(38):8233-8242. doi: 10.1523/JNEUROSCI.0649-18.2018. Epub 2018 Aug 9.
  • Fasting Activates Fatty Acid Oxidation to Enhance Intestinal Stem Cell Function during Homeostasis and Aging. Mihaylova MM, Cheng CW, Cao AQ, Tripathi S, Mana MD, Bauer-Rowe KE, Abu-Remaileh M, Clavain L, Erdemir A, Lewis CA, Freinkman E, Dickey AS, La Spada AR, Huang Y, Bell GW, Deshpande V, Carmeliet P, Katajisto P, Sabatini DM, Yilmaz ÖH. Cell Stem Cell. 2018 May 3;22(5):769-778.e4.

  • Therapy development in Huntington disease: From current strategies to emerging opportunities. Dickey AS, La Spada AR. Am J Med Genet A. 2018 Apr;176(4):842-861. doi: 10.1002/ajmg.a.38494. Epub 2017 Dec 8. Review.

  • PPARδ activation by bexarotene promotes neuroprotection by restoring bioenergetic and quality control homeostasis. Dickey AS, Sanchez DN, Arreola M, Sampat KR, Fan W, Arbez N, Akimov S, Van Kanegan MJ, Ohnishi K, Gilmore-Hall SK, Flores AL, Nguyen JM, Lomas N, Hsu CL, Lo DC, Ross CA, Masliah E, Evans RM, La Spada AR. Sci Transl Med. 2017 Dec 6;9(419). pii: eaal2332. doi: 10.1126/scitranslmed.aal2332.

  • PPAR-δ is repressed in Huntington's disease, is required for normal neuronal function and can be targeted therapeutically. Dickey AS, Pineda VV, Tsunemi T, Liu PP, Miranda HC, Gilmore-Hall SK, Lomas N, Sampat KR, Buttgereit A, Torres MJ, Flores AL, Arreola M, Arbez N, Akimov SS, Gaasterland T, Lazarowski ER, Ross CA, Yeo GW, Sopher BL, Magnuson GK, Pinkerton AB, Masliah E, La Spada AR. Nat Med. 2016 Jan;22(1):37-45. doi: 10.1038/nm.4003. Epub 2015 Dec 7.

  • PKA/AKAP1 and PP2A/Bβ2 regulate neuronal morphogenesis via Drp1 phosphorylation and mitochondrial bioenergetics. Dickey AS, Strack S. J Neurosci. 2011 Nov 2;31(44):15716-26. doi: 10.1523/JNEUROSCI.3159-11.2011.

  • Mechanism of neuroprotective mitochondrial remodeling by PKA/AKAP1. Merrill RA, Dagda RK, Dickey AS, Cribbs JT, Green SH, Usachev YM, Strack S. PLoS Biol. 2011 Apr;9(4):e1000612. doi: 10.1371/journal.pbio.1000612. Epub 2011 Apr 19.

View Dr. Dickey's complete publication history on Pubmed.